Perform the following actions to unlock the Alternate Attire, matches and more..
| Unlockable | How to unlock |
| Brand Warfare | - |
| The Hardys Entrance, DX Entrance, Morrison and the Miz Entrance | In Week 2, you must win the battle royal as either Triple H or John Cena |
| John Cena Alternate Attire (Street Clothes) | Week 4, you must put Kane through a table in less than 2:30 as John Cena |
| Triple H Alternate Attire (DX) | Week 6, win your match in under 3 minutes as Triple H |
| Alternate Attire for Miz and Morrison (Street clothes), Dirt Sheet area for backstage | Week 11, win the handicap match as either Triple H or John Cena |
| Champion of Champions Title Belt | Win at Wrestlemania |
| CAW RTW | - |
| Ezekiel Jackson | Week 3, throw each opponent out of the ring at least once. |
| Alternate attire for Mr. McMahon (suit) | Week 5, Spend at least one minute of the match outside the ring |
| Vinces Office in Backstage match | Week 6, win your match |
| Santino Marella Story Designer story | Week 11, reach 500 degrees at least four times |
| Alternate Attire for Santino Marella (Street clothes) | Week 12, make a successful diving attack from the top of the ladder |
| Alternate Attire for Vince McMahon (Chicken Head) | Win the WrestleMania Match |
| Edges RTW | - |
| Jesse | Week 2, hit every opponent with a finisher |
| Alternate Attire for Mr. Kennedy | Eliminate Mr. Kennedy from the Royal Rumble Match |
| Alternate Attire for Edge | Week 6, Win in under 3 minutes |
| Locker Room Backstage area | At No Way Out, drag Mr. Kennedy on top of the Big Show and count the pinfall |
| Mr. McMahon (Playable Character) | Week 11, Put Triple H through an announce table |
| The Rock | Complete Edges Road to Wrestlemania |
| Dickie James RTW | - |
| Eve | Week 2, pin or submit Maryse |
| Alternate Attire for Dickie James | Week 6, beat Michelle McCool in under 3 minutes |
| Alternate Attire for Natalya | Week 9, Choose Kendrick over natalya / Week 10, win the match suffering minimal damage |
| Alternate Attire for The Brian Kendrick | Week 9, choose Natalya over Kendrick / Week 12, win the match without using a signature move or finisher |
| Trish Stratus | Complete Mickies Road to Wrestlemania |
| Randy Orton's RTW | - |
| Green and Red (Dummies as Characters) | Week 3, refuse Codys help and then reverse three of Batista's attacks. |
| Randy Ortons Alternate Attire | At No Way Out, RKO Dusty Rhodes |
| Cowboy Bob Orton | Week 9, dont use any strikes in your match |
| Road to Wrestlemania Event Skip Feature (?) | Week 12, Spend less than 2 minutes in the ring as the legal superstar |
| Dusty Rhodes | Beat Cody Rhodes at WrestleMania and KO Dusty after the match |
| Ted DiBiase Sr. | Beat Ted DiBiase Jr. at Wrestlemania and KO Sr. after the match |
| HBK's RTW | - |
| Alternate Attire for Shawn Michaels | Week 4, hit both opponents with Sweet CHIN Music |
| Alternate Attire for Chris Jericho | Week 6, Make Jericho Bleed |
| Alternate Attire for JBL | Week 8, Win the match in under 4 minutes |
| Alternate Attire for Shawn Michaels (DX) | Week 10, Accept the Retirement Match / Week 11, have your partner be the legal man longer |+|OR|+| Week 10, Decline the Retirement Match / Week 11, Execute 3 Double Team attacks |
| Interview Room for Backstage | Complete Shawn Michaels RTW |