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Players will assume the identity of Ethan Thomas, the former Special Crimes Unit investigator, who's been called back to duty to track down his missing partner.

The disturbing events from Ethan's past have left him a broken man – a desperate burnout, drifting aimlessly through a society in inexplicable decline. Fighting inner demons throughout his one-man investigation into a sinister conspiracy, Ethan will need to use anything and everything in the environment to survive as he unravels the mysteries shrouding the city in darkness. [1]

Condemned 2 begins about one year after the events that occurred in the previous installment, Condemned: Criminal Origins. The many strange and unexplainable things that happened to Ethan in the past have left him a desperate burnout, homeless, and a drunk. Killing about 200 people in the first game, Ethan is now prone to many more hallucinations and strange visions that are mostly made up in his mind. It has been confirmed that the fact that Ethan has become an alcoholic will somehow be played into the storyline, but any details on the subject have not yet surfaced.

Greg Grunberg will not be voicing Ethan in Condemned 2 mostly due to the personality change. [2]