I am unable to save after winning missions. Made it as far as Serena St. Germaine, but can't save even after winning.
Anyone have any info. I am using only x-box controllers, and unplugged all of the other controllers.

I got past the part you are talking about last night, I didn't have any problems.

However they do ask too many questions at the end of a mission. They should have an auto save, and just never wipe out your stats with lower numbers.

Make sure that you pick save and if you already had a game there that your overwrite it... that's about all I can think of unless it actually is some glitch.